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Equine Protozoal Myeloencephalitis (EPM)
(Opossum Disease)

EPM mimics many other neurological conditions. However, the neurological symptoms associated with EPM can include the following:

  • Lameness or weakness
  • A lack of coordination and difficulty in moving
  • A loss of balance
  • Seizures

Accurate diagnosis of EPM is difficult because of the numerous similarities to other neurological conditions. The primary parasite that causes the disease is a single-celled protozoan organism, Sarcocystis Neurona.

In addtion, because of IFA (immunofluorescence assay) cross-reactivity, blood tests by IFA have limited values for diagnosis. A more accurate alternative is the cerebrospinal fluid (CSF) western blot test. However, it is very expensive, and collecting a sample exposes the patient and the veterinarian to unnecessary risks.


Current Therapies

The use of Karbo Combo+ has, in field studies, has proven very effective in helping the immune system combat the symptoms of EPM.

Karbo Combo+ consists of encapsulated enzymes, vitamins, bacteria, and large numbers of mannan, and glucan oligosaccharides. In addition, the formula also contains glycocomponents necessary for tying up and neutralizing various toxins.

The objective of Karbo Combo+ is to attach and bind to the surface lectins of pathogenic viruses, bacteria, protozoa, and toxins, therefore rendering them incapable of colonization and reproduction. The stimulation and modulation of the complex immune system by this formulation is not clearly understood at this time.